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Invitrogen
PDHA1/PDHA2 Polyclonal Antibody
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FIGURE: 1 / 4
PDHA1/PDHA2 Antibody (PA5-17190) in WB
Western blot was performed using Anti-PDHA1/PDHA2 Polyclonal Antibody (Product # PA5-17190) and a band at ~43 kDa corresponding to PDH was observed in all the cell lines and tissues tested. Whole cell extracts (30 µg lysate) of Hep G2 (Lane 1), HEK 293 (Lane 2), MDA-MB-231 (Lane 3), HL-60 (Lane 4), SK-OV-3 (Lane 5), PC-3 (Lane 6), PANC-1 (Lane 7), Mouse Liver (Lane 8), Rat Liver (Lane 9), Mouse Brown Adipose (Lane 10), Mouse Brain (Lane 11) were electrophoresed using Novex® NuPAGE® 4-12% % Bis-Tris gel (Product # NP0322BOX). Resolved prote... View More
Product Details
PA5-17190
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the sequences of both a1 and a2 subunits of human pyruvate dehydrogenase
Conjugate
Form
Liquid
Concentration
56 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, and thereby links the glycolytic pathway to the tricarboxylic cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PDHE1-A type I; PDHE1-A type II; pyruvate dehydrogenase complex, E1-alpha polypeptide 1; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 alpha 2; PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT, TESTIS-SPECIFIC FORM, MITOCHONDRIAL PRECURSOR (PDHE1-A TYPE II); Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; pyruvate dehydrogenase E1 subunit; pyruvate dehydrogenase E1alpha subunit; pyruvate dehydrogenase, E1-alpha polypeptide, testis specific
Gene Aliases: PDHA; Pdha-1; Pdha-2; PDHA1; PDHA2; PDHAD; PDHAL; PDHCE1A; PHE1A
UniProt ID: (Human) P08559, (Human) P29803, (Mouse) P35486, (Mouse) P35487, (Rat) Q06437
Entrez Gene ID: (Human) 5160, (Human) 5161, (Rat) 29554, (Mouse) 18597, (Mouse) 18598, (Rat) 117098
glucose metabolic process
acetyl-CoA biosynthetic process from pyruvate
pyruvate metabolic process
tricarboxylic acid cycle
regulation of acetyl-CoA biosynthetic process from pyruvate
glyoxylate metabolic process
mitochondrial acetyl-CoA biosynthetic process from pyruvate
glycolytic process
oxidation-reduction process
carbohydrate metabolic process
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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