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Proteintech
PDHB Polyclonal Antibody
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Product Details
14744-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Bat,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PDHB Fusion Protein Ag6442 (1-359 aa encoded by BC000439)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAVSGLVR RPLREVSGLL KRRFHWTAPA ALQVTVRDAI NQGMDEELER DEKVFLLGEE VAQYDGAYKV SRGLWKKYGD KRIIDTPISE MGFAGIAVGA AMAGLRPICE FMTFNFSMQA IDQVINSAAK TYYMSGGLQP VPIVFRGPNG ASAGVAAQHS QCFAAWYGHC PGLKVVSPWN SEDAKGLIKS AIRDNNPVVV LENELMYGVP FEFPPEAQSK DFLIPIGKAK IERQGTHITV VSHSRPVGHC LEAAAVLSKE GVECEVINMR TIRPMDMETI EASVMKTNHL VTVEGGWPQF GVGAEICARI MEGPAFNFLD APAVRVTGAD VPMPYAKILE DNSIPQVKDI IFAIKKTLNI (1-359 aa encoded by BC000439)
Target Information
PDHB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial) is also named as PHE1B. The enzyme, which is found in mitochondria, is one of the component enzymes of the pyruvate dehydrogenase multienzyme complex (PDH). It catalyzes the first reaction of an oxidative decarboxylation sequence converting pyruvate to acetyl-CoA and CO(2). Defects in PDHB are the cause of pyruvate dehydrogenase E1-beta deficiency (PDHBD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PDHE1-B; Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; pyruvate dehydrogenase, E1 beta polypeptide
Gene Aliases: 2610103L06Rik; AL024199; C81408; PDHB; PDHBD; PDHE1-B; PHE1B
UniProt ID: (Human) P11177, (Rat) P49432, (Mouse) Q9D051
Entrez Gene ID: (Human) 5162, (Rat) 289950, (Mouse) 68263
glucose metabolic process
acetyl-CoA biosynthetic process from pyruvate
pyruvate metabolic process
tricarboxylic acid cycle
regulation of acetyl-CoA biosynthetic process from pyruvate
glyoxylate metabolic process
mitochondrial acetyl-CoA biosynthetic process from pyruvate
carbohydrate metabolic process
metabolic process
oxidation-reduction process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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