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Invitrogen
PDK3 Polyclonal Antibody
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Product Details
PA5-28019
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Amphibian,
Human,
Mouse,
Rodent
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PDK3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HepG2, mouse liver, PDK3-transfected 293T.
Predicted reactivity: Mouse (96%), Rat (96%), Chicken (93%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 3; Pyruvate dehydrogenase kinase isoform 3; pyruvate dehydrogenase kinase, isoenzyme 3; pyruvate dehydrogenase kinase, isozyme 3; pyruvate dehydrogenase, lipoamide, kinase isozyme 3, mitochondrial
Gene Aliases: 2610001M10Rik; AI035637; CMTX6; GS1-358P8.4; PDHK3; PDK3
UniProt ID: (Human) Q15120, (Mouse) Q922H2
Entrez Gene ID: (Human) 5165, (Mouse) 236900
glucose metabolic process
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of glucose metabolic process
peptidyl-serine phosphorylation
peroxisome proliferator activated receptor signaling pathway
cellular response to glucose stimulus
cellular response to fatty acid
hypoxia-inducible factor-1alpha signaling pathway
regulation of reactive oxygen species metabolic process
carbohydrate metabolic process
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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