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Invitrogen
PDLIM3 Polyclonal Antibody
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FIGURE: 1 / 1
PDLIM3 Antibody (PA5-92915) in WB
Western blot analysis of PDLIM3 in extracts of Mouse lung. Samples were incubated with PDLIM3 Polyclonal antibody (Product # PA5-92915) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-92915
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 70-230 of human PDLIM3 (NP_0011075791)
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Amount
38 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KAAAHQLCLK IDRGETHLWS PQVSEDGKAH PFKINLESEP QEFKPIGTAH NRRAQPFVAA ANIDDKRQVV SASYNSPIGL YSTSNIQDAL HGQLRGLIPS SPQNEPTASV PPESDVYRML HDNRNEPTQP RQSGSFRVLQ GMVDDGSDDR PAGTRSVRAP V; Positive Samples: Mouse lung; Cellular Location: Cytoplasm, Z line, myofibril, sarcomere
Target Information
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actinin alpha 2 associated LIM protein; Actinin-associated LIM protein; Alpha-actinin-2-associated LIM protein; PDZ and LIM domain protein 3
Gene Aliases: Actn2lp; AI463105; ALP; Pdlim3
UniProt ID: (Mouse) O70209
Entrez Gene ID: (Mouse) 53318
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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