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Invitrogen
PDLIM7 Polyclonal Antibody
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FIGURE: 1 / 14
PDLIM7 Antibody (PA5-100026) in ICC/IF
Immunofluorescent analysis of PDLIM7 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and PDLIM7 polyclonal antibody (Product # PA5-100026) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-100026
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PDLIM7(Accession Q9NR12), corresponding to amino acid residues R17-Q67.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PDLIM7.
Target Information
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1110003B01Rik; enigma (LIM domain protein); LIM domain protein; LIM mineralization protein; LIM mineralization protein 2; Lim mineralization protein 3; LMP; PDZ and LIM domain 7 (enigma); PDZ and LIM domain protein 7; Protein enigma
Gene Aliases: ENIGMA; Lim1; LMP; LMP1; LMP3; PDLIM7
UniProt ID: (Human) Q9NR12, (Mouse) Q3TJD7, (Rat) Q9Z1Z9
Entrez Gene ID: (Human) 9260, (Mouse) 67399, (Rat) 286908
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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