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PDZD2 Antibody (PA5-104478) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded PDZD2 in human lymph node tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with PDZD2 polyclonal antibody (Product # PA5-104478) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-104478
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PDZD2(Accession O15018), corresponding to amino acid residues E67-G117.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2853779
Product Specific Information
Antibody detects endogenous levels of total PDZD2.
Target Information
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signaling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activated in prostate cancer protein; PDZ domain containing 3; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Plakophilin-related armadillo repeat protein-interacting PDZ protein; plakophilin-related armadillo repeat protein-interactive PDZ protein
Gene Aliases: 4930537L06Rik; A930022H17Rik; AIPC; Gm82; KIAA0300; mKIAA0300; PAPIN; PDZD2; PDZK3; PIN1
UniProt ID: (Human) O15018, (Rat) Q9QZR8
Entrez Gene ID: (Human) 23037, (Rat) 65034, (Mouse) 68070
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