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Proteintech
CD154 Monoclonal Antibody (MR1), PE
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FIGURE: 1 / 3
CD154 Antibody (PE-65129-100UG) in Flow
1X10^6 PMA (50 ng/mL) and ionomycin (1 µg/mL)-stimulated Mouse lymphoid cells (6 hours) were surface stained with APC Anti-Mouse CD4 (GK1.5) (APC-65104, Clone: GK1.5) and 0.06 µg PE Anti-Mouse CD154 (Product # PE-65129-100UG), Clone: MR1). Cells were not fixed.
Product Details
PE-65129-100UG
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Hamster
/ IgG
Class
Monoclonal
Type
Antibody
Clone
MR1
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
0.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.1% gelatin
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
Target Information
CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD154; CD40 ligand; CD40-L; H-CD-40-L; M-CD-40-L; RP23-153G22.3; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5
Gene Aliases: CD154; CD40-L; Cd40l; Cd40lg; gp39; HIGM1; IGM; IMD3; Ly-62; Ly62; T-BAM; Tnfsf5; TRAP
UniProt ID: (Mouse) P27548
Entrez Gene ID: (Mouse) 21947
positive regulation of immune response to tumor cell
inflammatory response
immune response
signal transduction
platelet activation
B cell differentiation
positive regulation of B cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
B cell proliferation
negative regulation of apoptotic process
isotype switching
positive regulation of MHC class II biosynthetic process
immunoglobulin secretion
regulation of immunoglobulin secretion
dendritic cell differentiation
positive regulation of endothelial cell apoptotic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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