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PEG3 Antibody (PA5-116550) in IHC (P)
Immunohistochemistry analysis of PEG3 in paraffin-embedded mouse brain. Samples were incubated with PEG3 Polyclonal antibody (Product # PA5-116550) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116550
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 195-400 of human PEG3 (NP_0062011)
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901181
Product Specific Information
Positive Samples: HepG2
Immunogen sequence: LSLPVVAKTS FEMDREDDRD SRAYESRSQD AESYQNVVDL AEDRKPHNTI QDNMENYRKL LSLVQLAEDD GHSHMTQGHS SRSKRSAYPS TSRGLKTMPE AKKSTHRRGI CEDESSHGVI MEKFIKDVSR SSKSGRARES SDRSQRFPRM SDDNWKDISL NKRESVIQQR VYEGNAFRGG FRFNSTLVSR KRVLERKRRY HFDTDG
Target Information
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASF-1; granule cell antiserum positive 4; Kruppel-type zinc finger protein; paternally expressed gene 3; Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24
Gene Aliases: AL022617; ASF-1; End4; Gcap4; KIAA0287; mKIAA0287; PEG3; PW1; Zfp102; ZKSCAN22; ZNF904; ZSCAN24
UniProt ID: (Human) Q9GZU2, (Mouse) Q3URU2
Entrez Gene ID: (Human) 5178, (Mouse) 18616
Performance Guarantee
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