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PELO Polyclonal Antibody
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FIGURE: 1 / 6
PELO Antibody (PA5-31697) in ICC/IF
PELO Polyclonal Antibody detects PELO protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PELO protein stained by PELO Polyclonal Antibody (Product # PA5-31697) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-31697
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PELO. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, HeLa, HepG2, PC-12, Rat2, , Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12.
Predicted reactivity: Human (99%), Mouse (97%), Rat (97%), Zebrafish (82%), Xenopus laevis (83%), Chicken (95%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PELO encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alternatively spliced; cell-cycle protein; hPelota; pelota homolog; Protein Dom34 homolog; Protein pelota homolog; unnamed protein product
Gene Aliases: AA409897; AI852218; CGI-17; PELO; PRO1770
UniProt ID: (Human) Q9BRX2, (Mouse) Q80X73, (Rat) Q5XIP1
Entrez Gene ID: (Human) 53918, (Mouse) 105083, (Rat) 294754
protein binding
ribosome binding
metal ion binding
nucleoside-triphosphatase regulator activity
stalled ribosome sensor activity
nuclease activity
endonuclease activity
hydrolase activity
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
translation release factor
inner cell mass cell proliferation
regulation of translation
endoderm development
stem cell population maintenance
positive regulation of BMP signaling pathway
ribosome disassembly
chromosome organization
cell division
mesenchymal to epithelial transition
nuclear-transcribed mRNA catabolic process, non-stop decay
nonfunctional rRNA decay
nuclear-transcribed mRNA catabolic process, no-go decay
RNA surveillance
rescue of stalled ribosome
cell cycle
cell proliferation
nucleic acid phosphodiester bond hydrolysis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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