Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-59961
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
1:20-1:50 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human PEMT |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.05 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2645383 |
Product Specific Information
Immunogen sequence: GFAGTFLGDY FGILKEARVT VFPFNILDNP MYWGSTANYL GWAIM
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
Target Information
This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: MGC2483; PEAMT; PEMT2; Phosphatidylethanolamine N-methyltransferase; Phospholipid methyltransferase; PLMT
Gene Aliases: PEAMT; PEMPT; PEMT; PEMT2; PNMT
UniProt ID: (Human) Q9UBM1
Entrez Gene ID: (Human) 10400
Molecular Function:
methyltransferase
transferase
metabolite interconversion enzyme
lipid metabolic process
glycerophospholipid metabolic process
phosphatidylcholine biosynthetic process
cell proliferation
negative regulation of cell proliferation
phospholipid biosynthetic process
methylation
response to vitamin
response to drug
response to amino acid
response to ethanol
S-adenosylhomocysteine metabolic process
S-adenosylmethionine metabolic process
positive regulation of lipoprotein metabolic process
positive regulation of protein targeting to mitochondrion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support