Invitrogen

PENK Polyclonal Antibody

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PENK Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of PENK in human adrenal gland using a PENK Polyclonal Antibody (Product # PA5-53021) shows strong cytoplasmic positivity in glandular medulla cells.

PENK Antibody in Western Blot (WB) — Western blot analysis of PENK in control (vector only transfected HEK293T lysate) and PENK over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a PENK Polyclonal Antibody (Product # PA5-53021).

Product Details

Tested Applications

Dilution

Immunohistochemistry (IHC)

1:1000-1:2500

Western Blot (WB)

0.4 µg/mL

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PENK

Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2645384

Product Specific Information

Immunogen sequence: ECSQDCATCS YRLVRPADIN FLACVMECEG KLPSLKIWET CKELLQLSKP ELPQDGTSTL RENSKPEESH LLAKRYGGFM KRYGGFMKKM DELYPMEPEE EANGSEILAK RYGGFMKKDA EE

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.

Target Information

neuropeptide hormone; plays a role in the responses to stress and pain perception.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: enkephalin A; Leu-enkephalin; Met-enkephalin; Met-enkephalin-Arg-Gly-Leu; Met-enkephalin-Arg-Phe; OGF; Opioid growth factor; PENK(114-133); PENK(143-183); PENK(237-258); preproenkephalin; Proenkephalin-A; Synenkephalin

Gene Aliases: PE; PENK; PENK-A

UniProt ID: (Human) Q6FHE6

Entrez Gene ID: (Human) 5179

Molecular Function: neuropeptide peptide hormone signaling molecule