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Invitrogen
PEO1 Polyclonal Antibody
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FIGURE: 1 / 2
PEO1 Antibody (PA5-92383) in WB
Western blot analysis of PEO1 in extracts of various cell lines. Samples were incubated with PEO1 Polyclonal antibody (Product # PA5-92383) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-92383
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 135-335 of human C10orf2 (NP_0686022)
Conjugate
Form
Liquid
Concentration
1.92 mg/mL
Amount
192 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GAREGFLLSK APEFEDSEEV RRIWNRAIPL WELPDQEEVQ LADTMFGLTK VTDDTLKRFS VRYLRPARSL VFPWFSPGGS GLRGLKLLEA KCQGDGVSYE ETTIPRPSAY HNLFGLPLIS RRDAEVVLTS RELDSLALNQ STGLPTLTLP RGTTCLPPAL LPYLEQFRRI VFWLGDDLRS WEAAKLFARK LNPKRCFLVR P
Positive Samples: MCF7; Cellular Location: Mitochondrion matrix, mitochondrion nucleoid
Target Information
Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ataxin 8; Ataxin8; ATXN 8; C10 orf2; C10orf 2; FLJ21832; PEO 1; progressive external ophthalmoplegia 1 homolog; Progressive external ophthalmoplegia 1 protein; Progressive external ophthalmoplegia 1 protein homolog; SCA 8; T7 gp4-like protein with intramitochondrial nucleoid localization; T7 helicase-related protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; Twinkle mtDNA helicase; Twinkle protein, mitochondrial; unnamed protein product
Gene Aliases: ATXN8; C10orf2; D19Ertd626e; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL; TWNK
UniProt ID: (Mouse) Q8CIW5, (Human) Q96RR1
Entrez Gene ID: (Mouse) 226153, (Rat) 309441, (Human) 56652
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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