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Invitrogen
Rat Ghrelin (aa 252-267) Synthetic Peptide
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Product Details
PEP-290
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
50 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-290 is a 23 amino acid synthetic peptide whose sequence is derived from the rat Obestatin. The sequence of this peptide is (amino to carboxy terminus): F-N-A-P-F-D-V-G-I-K-L-S-G-A-Q-Y-Q-Q-H-G-R-A-L
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, Obestatin, catalog # PA1-1070. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Target Information
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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