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Search Thermo Fisher Scientific
Immunogen sequence: LYQLLNLHY PPKLEGQAQA EAKAGEGTYA LDSESCMEKL AALSASLARV VVPATEEEAE VDEFPTDGEM SAQEEDRRKE LEAQEKHKKL FEGLKFFLNR EVPREALAFI IRSFGGEVSW DKSLCIGATY DVTDSRITHQ IVDRPGQQTS VIGRCYVQPQ WVFDSVNARL LLPVAEYFSG VQLPPHLSPF VTEKEGDYVP PEKLKLLALQ RGEDPGNLNE SEEEEEEDDN NEGDGDEEGE NEEEEEDAEA GSEKEEEARL AALEEQRMEG KKPRVMAGTL KLEDKQRLAQ EEESEAKRLA IMMMKKREKY LYQKIMFGKR RKIREANKLA EKRKAHDEAV RSEKKAKKAR PE (238-588 aa encoded by BC032489)
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
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Protein Aliases: PES1; Pescadillo homolog; pescadillo homolog 1, containing BRCT domain
Gene Aliases: PES; PES1
UniProt ID: (Human) O00541
Entrez Gene ID: (Human) 23481
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