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Proteintech
PEX14 Polyclonal Antibody
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Product Details
10594-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PEX14 Fusion Protein Ag0932 (77-377 aa encoded by BC006327)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can be used to detect endogenous PEX14 with an apparent molecular weight of 57 kDa and recognize peroxisomal structures in human, monkey and mouse cells.
Immunogen sequence: PSSLGPATQ VVPVQPPHLI SQPYSPAGSR WRDYGALAII MAGIAFGFHQ LYKKYLLPLI LGGREDRKQL ERMEAGLSEL SGSVAQTVTQ LQTTLASVQE LLIQQQQKIQ ELAHELAAAK ATTSTNWILE SQNINELKSE INSLKGLLLN RRQFPPSPSA PKIPSWQIPV KSPSPSSPAA VNHHSSSDIS PVSNESTSSS PGKEGHSPEG STVTYHLLGP QEEGEGVVDV KGQVRMEVQG EEEKREDKED EEDEEDDDVS HVDEEDCLGV QREDRRGGDG QINEQVEKLR RPEGASNESE RD (77-377 aa encoded by BC006327)
Target Information
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; peroxisomal protein Pex14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein
Gene Aliases: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p; R75137
UniProt ID: (Human) O75381, (Mouse) Q9R0A0, (Rat) Q642G4
Entrez Gene ID: (Human) 5195, (Mouse) 56273, (Rat) 64460
protein complex assembly
peroxisome organization
protein import into peroxisome matrix
protein import into peroxisome matrix, translocation
negative regulation of protein binding
microtubule anchoring
peroxisome transport along microtubule
negative regulation of sequence-specific DNA binding transcription factor activity
protein import into peroxisome matrix, substrate release
negative regulation of transcription, DNA-templated
protein homooligomerization
negative regulation of protein homotetramerization
transport
protein transport
protein import into peroxisome matrix, docking
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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