Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:2,000-1:10,000 | View 5 publications 5 publications |
Immunohistochemistry (IHC) |
- | View 4 publications 4 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 14 publications 14 publications |
Flow Cytometry (Flow) |
0.2 µg/1x10^6 cells | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Artificial Control, Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
PEX14 Fusion Protein Ag0932 (77-377 aa encoded by BC006327) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.33 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
This antibody can be used to detect endogenous PEX14 with an apparent molecular weight of 57 kDa and recognize peroxisomal structures in human, monkey and mouse cells.
Immunogen sequence: PSSLGPATQ VVPVQPPHLI SQPYSPAGSR WRDYGALAII MAGIAFGFHQ LYKKYLLPLI LGGREDRKQL ERMEAGLSEL SGSVAQTVTQ LQTTLASVQE LLIQQQQKIQ ELAHELAAAK ATTSTNWILE SQNINELKSE INSLKGLLLN RRQFPPSPSA PKIPSWQIPV KSPSPSSPAA VNHHSSSDIS PVSNESTSSS PGKEGHSPEG STVTYHLLGP QEEGEGVVDV KGQVRMEVQG EEEKREDKED EEDEEDDDVS HVDEEDCLGV QREDRRGGDG QINEQVEKLR RPEGASNESE RD (77-377 aa encoded by BC006327)
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; peroxisomal protein Pex14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein
Gene Aliases: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p; R75137
UniProt ID: (Human) O75381, (Mouse) Q9R0A0, (Rat) Q642G4
Entrez Gene ID: (Human) 5195, (Mouse) 56273, (Rat) 64460
Molecular Function:
primary active transporter
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