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Invitrogen
PEX14 Polyclonal Antibody
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FIGURE: 1 / 1
PEX14 Antibody (PA5-101742) in WB
Western blot analysis of PEX14 in extracts from various samples. Samples were incubated with PEX14 polyclonal antibody (Product # PA5-101742). Lane 1: Rat liver, blocked with antigen-specific peptides; Lane 2: Rat liver; Lane 3: Hela cells (heat-shock treatment).
Product Details
PA5-101742
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PEX14(Accession O75381), corresponding to amino acid residues P236-S286.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PEX14.
Target Information
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anchor protein for HsPex5p; NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; peroxisomal protein Pex14; PEX14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein; unnamed protein product
Gene Aliases: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p; R75137
UniProt ID: (Human) O75381, (Mouse) Q9R0A0, (Rat) Q642G4
Entrez Gene ID: (Human) 5195, (Mouse) 56273, (Rat) 64460
protein monoubiquitination
peroxisome organization
protein transport
protein import into peroxisome matrix
protein import into peroxisome matrix, docking
protein import into peroxisome matrix, translocation
protein import into peroxisome matrix, receptor recycling
negative regulation of protein binding
microtubule anchoring
cellular response to reactive oxygen species
peroxisome transport along microtubule
protein unfolding
negative regulation of sequence-specific DNA binding transcription factor activity
protein import into peroxisome matrix, substrate release
negative regulation of transcription, DNA-templated
protein-containing complex assembly
protein complex assembly
transport
protein homooligomerization
negative regulation of protein homotetramerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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