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Invitrogen
PEX14 Polyclonal Antibody
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FIGURE: 1 / 6
PEX14 Antibody (PA5-78103) in ICC/IF
PEX14 Polyclonal Antibody detects PEX14 protein at peroxisome by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PEX14 protein stained by PEX14 Polyclonal Antibody (Product # PA5-78103) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-78103
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PEX14. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: 293T, A431, HeLa, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2
Predicted Reactivity: Mouse (90%), Rat (90%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; peroxisomal protein Pex14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein
Gene Aliases: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p; R75137
UniProt ID: (Human) O75381, (Mouse) Q9R0A0, (Rat) Q642G4
Entrez Gene ID: (Human) 5195, (Mouse) 56273, (Rat) 64460
protein complex assembly
peroxisome organization
protein import into peroxisome matrix
protein import into peroxisome matrix, translocation
negative regulation of protein binding
microtubule anchoring
peroxisome transport along microtubule
negative regulation of sequence-specific DNA binding transcription factor activity
protein import into peroxisome matrix, substrate release
negative regulation of transcription, DNA-templated
protein homooligomerization
negative regulation of protein homotetramerization
transport
protein transport
protein import into peroxisome matrix, docking
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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