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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (QKPNLEGSVSHK) corresponding to the internal amino acids of PEX26|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5-1.5 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 . PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome , neonatal adrenoleukodystrophy , infantile Refsum disease , and classical rhizomelic chondrodysplasia punctata . Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FLJ20695; Peroxin-26; peroxisomal biogenesis factor 26; Peroxisome assembly protein 26; peroxisome biogenesis disorder, complementation group 8; peroxisome biogenesis disorder, complementation group A; peroxisome biogenesis factor 26; PEX26; PEX26M1T; Pex26pM1T
PBD7A; PBD7B; PEX26; PEX26M1T; Pex26pM1T