The synthetic peptide sequence is 85-101aa, DLQAPLYKKIIKKLLES
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; Endothelial cell growth inhibitor; Iroplact; Oncostatin-A; PF-4; Platelet factor 4; Platelet factor 4, short form; short form
Gene Aliases: CXCL4; PF-4; PF4; SCYB4
UniProt ID: (Human) P02776
Entrez Gene ID: (Human) 5196