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Product Details
H00065061-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PFTK2 (AAH38807.1, 1 a.a. approximately 349 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTSFHPRGLQ AARAQKFKSK RPRSNSDCFQ EEDLRQGFQW RKSLPFGAAS SYLNLEKLGE GSYATVYKGI SRINGQLVAL KVISMNAEEG VPFTAIREAS LLKGLKHANI VLLHDIIHTK ETLTFVFEYM HTDLAQYMSQ HPGGLHPHNV RLFMFQLLRG LAYIHHQHVL HRDLKPQNLL ISHLGELKLA DFGLARAKSI PSQTYSSEVV TLWYRPPDAL LGATEYSSEL DIWGAGCIFI EMFQGQPLFP GVSNILEQLE KIWEVLGVPT EDTWPGVSKL PNYNPEWFPL PTPRSLHVVW NRLGRVPEAE DLASQMLKGF PRDRVSAQEA LVHDYFSALP SQLYQLPDE
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 7; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; Cell division protein kinase 15; Cyclin-dependent kinase 15; PFTAIRE protein kinase 2; serine/threonine protein kinase; Serine/threonine-protein kinase ALS2CR7; Serine/threonine-protein kinase PFTAIRE-2
Gene Aliases: ALS2CR7; CDK15; PFTAIRE2; PFTK2
UniProt ID: (Human) Q96Q40
Entrez Gene ID: (Human) 65061
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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