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PGAM2 Polyclonal Antibody
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FIGURE: 1 / 3
PGAM2 Antibody (PA5-22038) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of PGAM2 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: PGAM2 Polyclonal Antibody (Product # PA5-22038) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker. Blue: Hoechst 33342 staining.
Product Details
PA5-22038
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Bacteria,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human PGAM2 Recombinant protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: H1299, HeLa, rat muscle.
Predicted reactivity: Mouse (92%), Rat (93%), Zebrafish (86%), Xenopus laevis (86%), Pig (96%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; PGAM-M; Phosphoglycerate mutase 2; phosphoglycerate mutase 2 (muscle); Phosphoglycerate mutase isozyme M
Gene Aliases: D14Mgh1; GSD10; PGAM-M; PGAM2; PGAMM; Pgmut
UniProt ID: (Human) P15259, (Rat) P16290
Entrez Gene ID: (Human) 5224, (Rat) 24959
catalytic activity
bisphosphoglycerate mutase activity
phosphoglycerate mutase activity
protein binding
hydrolase activity
isomerase activity
intramolecular transferase activity, phosphotransferases
identical protein binding
bisphosphoglycerate 2-phosphatase activity
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
cofactor binding
mutase
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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