Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Immunogen sequence: NWDRREPLSL INVRKRNVES GEEELASKLD HYKAKATRHI FLIRHSQYHV DGSLEKDRTL TPLGREQAEL TGLRLASLGL KFNKIV
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bcl-XL-binding protein v68; PGAM family member 5, serine/threonine protein phosphatase, mitochondrial; Phosphoglycerate mutase family member 5; Serine/threonine-protein phosphatase PGAM5, mitochondrial
Gene Aliases: BXLBV68; PGAM5
UniProt ID: (Human) Q96HS1
Entrez Gene ID: (Human) 192111
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