Recommended positive controls: A549, Mouse heart, Mouse lung.
Predicted reactivity: Mouse (91%), Rat (90%), Zebrafish (86%), Xenopus laevis (84%), Chicken (91%), Sheep (96%), Chimpanzee (99%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, decarboxylating; 6PGD; decarboxylating
Gene Aliases: 0610042A05Rik; 6PGD; AU019875; C78335; PGD; PGDH