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Invitrogen
PGF Polyclonal Antibody
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FIGURE: 1 / 2
PGF Antibody (PA5-95903) in WB
Western blot analysis of PGF in extracts of various cell lines. Samples were incubated with PGF Polyclonal antibody (Product # PA5-95903) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 120s.
Product Details
PA5-95903
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-170 of human PLGF (NP_0026232)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Amount
47 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR; Positive Samples: Mouse brain, Mouse liver
Target Information
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family. PlGF is a pleiotropic factor affects different cell types and regulates various biological responses. The activity of vascular endothelial growth factor (VEGF), which is the most potent of all angiogenic mediators, is partly modulated by PlGF. It plays a major role in vasculogenesis and angiogenesis in human placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PIGF; Placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein; PlGF; PlGF 1; SHGC; unnamed protein product
Gene Aliases: AI854365; D12S1900; PGF; PGFL; PIGF; PLGF; PlGF-2; SHGC-10760
UniProt ID: (Human) P49763, (Mouse) P49764, (Rat) Q63434
Entrez Gene ID: (Human) 5228, (Mouse) 18654, (Rat) 94203
angiogenesis
response to hypoxia
sprouting angiogenesis
signal transduction
cell-cell signaling
positive regulation of cell proliferation
cell differentiation
vascular endothelial growth factor signaling pathway
vascular endothelial growth factor receptor signaling pathway
positive chemotaxis
induction of positive chemotaxis
positive regulation of cell division
positive regulation of mast cell chemotaxis
branching involved in ureteric bud morphogenesis
positive regulation of endothelial cell proliferation
multicellular organism development
positive regulation of angiogenesis
regulation of morphogenesis of a branching structure
female pregnancy
organ regeneration
cellular response to hormone stimulus
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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