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Proteintech
PGLYRP4 Polyclonal Antibody
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Product Details
21134-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PGLYRP4 Fusion Protein Ag15539 (18-113 aa encoded by BC142636)
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Amount
66 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DSSWNKTQA KQVSEGLQYL FENISQLTEK GLPTDVSTTV SRKAWGAEAV GCSIQLTTPV NVLVIHHVPG LECHDQTVCS QRLRELQAHH VHNNSGC (18-113 aa encoded by BC142636)
Target Information
The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1, 2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4-5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; Peptidoglycan recognition protein intermediate beta; PGLYRPIbeta; PGRP-I-beta; unnamed protein product
Gene Aliases: PGLYRP4; PGLYRPIbeta; PGRP-Ibeta; PGRPIB; SBBI67
UniProt ID: (Human) Q96LB8
Entrez Gene ID: (Human) 57115
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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