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Product Details
12867-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
PHC2 Fusion Protein Ag3507 (1-323 aa encoded by BC028396) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.18 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MTSGNGNSA SSIAGTAPQN GENKPPQAIV KPQILTHVIE GFVIQEGAEP FPVGRSSLLV GNLKKKYAQG FLPEKLPQQD HTTTTDSEME EPYLQESKEE GAPLKLKCEL CGRVDFAYKF KRSKRFCSMA CAKRYNVGCT KRVGLFHSDR SKLQKAGAAT HNRRRASKAS LPPLTKDTKK QPTGTVPLSV TAALQLTHSQ EDSSRCSDNS SYEEPLSPIS ASSSTSRRRQ GQRDLELPDM HMRDLVGMGH HFLPSEPTKW NVEDVYEFIR SLPGCQEIEE EFRAQEIDGQ ALLLLKEDHL MSAMNIKLGP ALKIYARISM LKDS (1-323 aa encoded by BC028396)
Target Information
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: early development regulator 2; early development regulator 2 (homolog of polyhomeotic 2); Early development regulatory protein 2; hPH2; mPH2; p36; polyhomeotic 2; polyhomeotic 2 protein; polyhomeotic-like 2; Polyhomeotic-like protein 2
Gene Aliases: A3galt2; AA415044; D130050K19Rik; D4Ertd810e; EDR2; HPH2; Mph2; p36; PH2; PHC2
UniProt ID: (Human) Q8IXK0, (Mouse) Q9QWH1
Entrez Gene ID: (Human) 1912, (Mouse) 54383, (Rat) 313038
Molecular Function:
chromatin/chromatin-binding, or -regulatory protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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