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Product Details
PA5-65974
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human PHF15. Recombinant protein control fragment (Product #RP-106662).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664884
Product Specific Information
Immunogen sequence: IDGTFFNSWLA QSVQITAENM AMSEWPLNNG HREDPAPGLL SEELLQDEET LLSFMRDPSL RPGDPARKAR G
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.
Target Information
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase Jade-2; Jade family PHD finger protein 2; PHD finger protein 15
Gene Aliases: JADE-2; JADE2; KIAA0239; PHF15
UniProt ID: (Human) Q9NQC1
Entrez Gene ID: (Human) 23338
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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