This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ16355; MGC2941; novel PHD-finger protein JUNE1; PDH-containing protein JUNE-1; PHD finger protein 23; PHD finger protein 23a; PHD zinc finger containing protein JUNE1
Gene Aliases: BOS_18710; hJUNE-1b; JUNE-1; PHF23