The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
PHPT1 is an EDTA-insensitive phosphohistidine phosphatase that catalyzes the dephosphorylation of phosphopeptide I. Protein histidine phosphorylation and dephosphorylation in eukaryotes has been sparsely studied compared to protein serine/threonine and tyrosine phosphorylation, although protein histidine phosphorylation is estimated to account for about 6% of total protein phosphorylation in eukaryotes. Ek et al. (2002) detected no activity of PHPT1 towards phosphoserine, phosphothreonine, or phosphotyrosine peptides.
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Protein Aliases: 14 kDa phosphohistidine phosphatase; CGI-202; epididymis secretory sperm binding protein Li 132P; HSPC141; Phosphohistidine phosphatase 1; PHP; PHP14; PHPT1; Protein histidine phosphatase; Protein janus-A homolog; sex-regulated protein janus-a
Gene Aliases: 1700008C22Rik; CGI-202; HEL-S-132P; HSPC141; PHP14; PHPT1