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Proteintech
PHYHD1 Polyclonal Antibody
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Product Details
16125-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PHYHD1 Fusion Protein Ag9108 (1-297 aa encoded by BC009373)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MACLSPSQL QKFQQDGFLV LEGFLSAEEC VAMQQRIGEI VAEMDVPLHC RTEFSTQEEE QLRAQGSTDY FLSSGDKIRF FFEKGVFDEK GNFLVPPEKS INKIGHALHA HDPVFKSITH SFKVQTLARS LGLQMPVVVQ SMYIFKSPLI RTPPSCTRSP WAGCWACGSQ WRMPRWRTAV SGSSLAPTPV VCQGGWSGPL LAQRLVPASL GQSQPGITAS LCPPQCREGP WSSSMEKWYT RASRTSLTAR ARPTLSTSWR PLAPPGARRT GSSQQLNCPF PNCTPKGSRR AGALAPPG (1-297 aa encoded by BC009373)
Target Information
PHYHD1 (phytanoyl-CoA dioxygenase domain containing 1) is a 291 amino acid protein belonging to the PHYH family and the PHYHD1 subfamily. Encoded by a gene that maps to human chromosome 9q34.11, PHYHD1 exists as three alternatively spliced isoforms and likely functions as an alpha-ketoglutatare-dependent dioxygenase. PHYHD1 participates in metal ion binding and oxidoreductase activity, thereby acting on single donors with incorporation of two atoms of oxygen. Related to PHYH (phytanoyl-CoA 2-hydroxylase), an Fe(II) and 2-oxoglutarate (2OG)-dependent oxygenase that catalyzes the initial alpha-oxidation step in the degradation of phytenic acid in peroxisomes, PHYHD1 similarly exhibits additional homologues in a wide range of metazoans and bacteria. PHYHD1 also may play a role in DNA methylation in early postnatal liver development and mammalian differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Phytanoyl-CoA dioxygenase domain-containing protein 1; Protein PHYHD1; unnamed protein product
Gene Aliases: PHYHD1
UniProt ID: (Human) Q5SRE7, (Mouse) Q9DB26, (Rat) Q5BJP9
Entrez Gene ID: (Human) 254295, (Mouse) 227696, (Rat) 296621
protein binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
metal ion binding
dioxygenase activity
molecular_function
N-ethylmaleimide reductase activity
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
epoxyqueuosine reductase activity
oxygenase
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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