Immunogen sequence: PPTNNFTDIE AALKAQLDSA DIPKARRKRY ISQNDMIAIL DYHNQVRGKV
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Predicted homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 91%
This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system. [provided by RefSeq].
Protein Aliases: 25 kDa trypsin inhibitor; CRISP-8; Cysteine-rich secretory protein 8; DKFZp686F0366; p25TI; Peptidase inhibitor 15; PI-15; protease inhibitor 15; SugarCrisp
Gene Aliases: CRISP8; P24TI; P25TI; PI15
UniProt ID: (Human) Q68CY1
Entrez Gene ID: (Human) 51050
Molecular Function: defense/immunity protein