This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Two transcript variants encoding different isoforms have been described for this gene.
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Protein Aliases: phosphatidylinositol 4-kinase; Phosphatidylinositol 4-kinase alpha; PI4-kinase alpha
Gene Aliases: Pi4ka; Pik4; Pik4ca
UniProt ID: (Mouse) E9Q3L2
Entrez Gene ID: (Mouse) 224020