The synthetic peptide sequence is 636-651aa, DTASIFGIIPDIISLD
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AR interacting protein; DDXBP1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein transferase PIAS1; GBP; Gu-binding protein; PIAS1; Protein inhibitor of activated STAT protein 1; protein inhibitor of activated STAT-1; RING-type E3 ubiquitin transferase PIAS1; RNA helicase II-binding protein; zinc finger, MIZ-type containing 3
Gene Aliases: 2900068C24Rik; DDXBP1; GBP; GU/RH-II; PIAS1; ZMIZ3
Molecular Function: ligase