|Immunohistochemistry (Paraffin) (IHC (P))||1.25 - 2.5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from internal region of human PIGR.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Orangutan, Gibbon (89%).
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
Protein Aliases: hepatocellular carcinoma associated protein TB6; Hepatocellular carcinoma-associated protein TB6; PIGR; Poly-Ig receptor; Polymeric immunoglobulin receptor
Gene Aliases: PIGR
UniProt ID: (Human) P01833
Entrez Gene ID: (Human) 5284