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Product Details
PA5-113078
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Phosphatidylinositol-glycan biosynthesis class W protein (392-448AA)
Conjugate
Unconjugated
Form
Liquid
Concentration
3.7 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
RRID
AB_2867812
Target Information
Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit various functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis including mannosylation of the GPI-anchor. PIG-W (Phosphatidylinositol-glycan biosynthesis class W protein) is a 504 amino acid multi-pass membrane protein that functions in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: phosphatidylinositol glycan anchor biosynthesis, class W; phosphatidylinositol glycan, class W; Phosphatidylinositol-glycan biosynthesis class W protein; PIG-W
Gene Aliases: Gwt1; HPMRS5; PIGW
UniProt ID: (Human) Q7Z7B1, (Rat) Q7TSN4
Entrez Gene ID: (Human) 284098, (Rat) 378774
Molecular Function:
acyltransferase
transferase
metabolite interconversion enzyme
Performance Guarantee
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