Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:4,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
PIGZ Fusion Protein Ag11259 (435-579 aa encoded by BC044640) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.23 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: LVPGLEYLE QVVHAPVLPS TPTHYTLLFT HTYMPPRHLL HLPGLGAPVE VVDIGGTEDW ALCQTLKSFT RQPACQVAGG PWLCRLFVVT PGTTRRAVEK CSFPFKNETL LFPHLTLEDP PALSSLLSGA WRDHLSLHIV ELGEET (435-579 aa encoded by BC044640)
The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dol-P-Man dependent GPI mannosyltransferase; GPI mannosyltransferase 4; GPI mannosyltransferase IV; GPI-MT-IV; hSMP3; phosphatidylinositol glycan anchor biosynthesis, class Z; phosphatidylinositol glycan, class Z; phosphatidylinositol glycan, class Z-like 1; Phosphatidylinositol-glycan biosynthesis class Z protein; PIG-Z; SMP3 homolog; SMP3 mannosyltransferase
Gene Aliases: F630022B06Rik; GPI-MT-IV; PIG-Z; PIGZ; RGD1307107; SMP3
UniProt ID: (Human) Q86VD9, (Mouse) Q8BTP0
Entrez Gene ID: (Human) 80235, (Mouse) 239827, (Rat) 303872
Molecular Function:
glycosyltransferase
transferase
metabolite interconversion enzyme
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