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Proteintech
PIH1D1 Polyclonal Antibody
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Product Details
19427-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PIH1D1 Fusion Protein Ag13759 (1-290 aa encoded by BC001108)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MANPKLLGL ELSEAEAIGA DSARFEELLL QASKELQQAQ TTRPESTQIQ PQPGFCIKTN SSEGKVFINI CHSPSIPPPA DVTEEELLQM LEEDQAGFRI PMSLGEPHAE LDAKGQGCTA YDVAVNSDFY RRMQNSDFLR ELVITIAREG LEDKYNLQLN PEWRMMKNRP FMGSISQQNI RSEQRPRIQE LGDLYTPAPG RAESGPEKPH LNLWLEAPDL LLAEIDLPKL DGALGLSLEI GENRLVMGGP QQLYHLDAYI PLQINSHESK AAFHRKRKQL MVAMPLLLVP S (1-290 aa encoded by BC001108)
Target Information
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dynein axonemal assembly factor 14; Nucleolar protein 17 homolog; PIH1 domain-containing protein 1; unnamed protein product
Gene Aliases: 1110061L23Rik; 4933413A04Rik; DNAAF14; MOT48; NOP17; Pih1; PIH1D1; RGD1309809
UniProt ID: (Human) Q9NWS0, (Mouse) Q9CQJ2, (Rat) Q4V7F5
Entrez Gene ID: (Human) 55011, (Mouse) 68845, (Rat) 292898
box C/D snoRNP assembly
chromatin remodeling
rRNA processing
epithelial cell differentiation
snoRNA localization
protein stabilization
positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
positive regulation of glucose mediated signaling pathway
regulation of TORC2 signaling
positive regulation of TORC1 signaling
TORC1 complex assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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