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PIK3R2 Polyclonal Antibody
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FIGURE: 1 / 3
PIK3R2 Antibody (600-401-R17) in IHC (P)
Immunohistochemistry analysis of PIK3R2 using anti-PIK3R2 antibody. PIK3R2 was detected in paraffin-embedded section of human mammary cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH 6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-PIK3R2 Antibody overnight at 4°C. ... View More
Product Details
600-401-R17
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PIK3R2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human PIK3R2.
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg thimerosal, 0.05mg sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3-kinase p85 subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K; PI3K regulatory subunit beta; ptdIns-3-kinase p85-beta; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta
Gene Aliases: MPPH; MPPH1; p85; p85-BETA; P85B; p85beta; PIK3R2
UniProt ID: (Human) O00459, (Mouse) O08908
Entrez Gene ID: (Human) 5296, (Mouse) 18709, (Rat) 29741
phosphotyrosine binding
GTPase activator activity
protein binding
protein phosphatase binding
receptor tyrosine kinase binding
phosphatidylinositol 3-kinase regulatory subunit binding
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
transcription factor binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol 3-kinase regulator activity
kinase modulator
cellular glucose homeostasis
immune response
signal transduction
insulin receptor signaling pathway
regulation of autophagy
protein transport
B cell differentiation
T cell differentiation
regulation of actin filament polymerization
cellular response to insulin stimulus
response to endoplasmic reticulum stress
positive regulation of protein import into nucleus
negative regulation of MAPK cascade
protein kinase B signaling
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
regulation of stress fiber assembly
regulation of protein localization to plasma membrane
transport
phosphatidylinositol 3-kinase signaling
regulation of phosphorylation
positive regulation of transcription factor import into nucleus
regulation of phosphatidylinositol 3-kinase activity
phosphatidylinositol phosphorylation
regulation of establishment of protein localization to plasma membrane
phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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