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Invitrogen
PIM1 Polyclonal Antibody
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Product Details
PA5-149507
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Partial recombinant protein made to an N-terminal portion of human PIM1 (between residues 1-200) [UniProt# P11309]
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The proto-oncogene PIM1 is upregulated in prostate cancer. PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Oncogene PIM1; pim-1 oncogene (proviral integration site 1); Pim-1L; proto-oncogene serine/threonine-protein kinase pim-1; Serine/threonine-protein kinase pim-1; unnamed protein product
Gene Aliases: PIM; PIM1
UniProt ID: (Human) P11309
Entrez Gene ID: (Human) 5292
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
transcription factor binding
kinase activity
transferase activity
manganese ion binding
ribosomal small subunit binding
protein serine/threonine kinase activator activity
metal ion binding
protein serine kinase activity
protein phosphorylation
apoptotic process
regulation of mitotic cell cycle
regulation of transmembrane transporter activity
cellular response to nutrient levels
cellular response to amino acid starvation
defense response to bacterium
negative regulation of apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of innate immune response
positive regulation of transcription, DNA-templated
protein autophosphorylation
protein stabilization
cytolysis in other organism
positive regulation of cardiac muscle cell proliferation
vitamin D receptor signaling pathway
cellular response to interferon-gamma
positive regulation of protein serine/threonine kinase activity
positive regulation of brown fat cell differentiation
non-canonical inflammasome complex assembly
regulation of hematopoietic stem cell proliferation
negative regulation of TORC1 signaling
positive regulation of TORC1 signaling
positive regulation of cardioblast proliferation
cellular detoxification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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