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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the N-terminal residues 1-50 of human PINK1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris citrate, pH 7-8|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Phosphatase and Tensin Homolog (PTEN) dephosphorylates lipids. Malfunctions in this contribute to many human cancers. PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers. It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BC 100-PINK1 (formerly part; PARK6; Pink1; protein kinase BRPK; PTEN-induced putative kinase protein 1; Serine/threonin-protein kinase PINK1 mitochondria [precursor]; serine/threonine-protein kinase PINK1, mitochondrial
1190006F07Rik; AU042772; AW557854; BRPK; mFLJ00387; PARK6; PINK1