This Antibody was verified by Cell Treatment to ensure that the antibody binds to the antigen stated. View Details
Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
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Protein Aliases: BRPK; PINK1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine kinase PINK1, mitochondrial [Precursor]; Serine/threonine-protein kinase PINK1, mitochondrial
Gene Aliases: 1190006F07Rik; AU042772; AW557854; BRPK; mFLJ00387; PARK6; PINK1