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Proteintech
PINX1 Polyclonal Antibody
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Product Details
12368-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PINX1 Fusion Protein Ag3043 (1-328 aa encoded by BC015479)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSMLAERRR KQKWAVDPQN TAWSNDDSKF GQRMLEKMGW SKGKGLGAQE HGATDHIKVQ VKNNHLGLGA TINNEDNWIA HQDDFNQLLA ELNTCHGQET TDSSDKKEKK SFSLEEKSKI SKNRVHYMKF TKGKDLSSRS KTDLDCIFGK RQSKKTPEGD ASPSTPEENE TTTTSAFTIQ EYFAKRMAAL KNKPQVPVPG SDISETQVER KRGKKINKEA TGKDVESYLQ PKAKRHTEGK PERAEAQERV AKKKSAPAEE QLRGPCWDQS SKASAQDAGD HVQPPEGRDF TLKPKKRRGK KKLQKPVEIA EDATLEETLV KKKKKKDSK (1-328 aa encoded by BC015479 )
Target Information
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 67-11-3 protein; FLJ20565; hepatocellular carcinoma-related putative tumor suppressor; Liver-related putative tumor suppressor; LPTS1; MGC8850; pin2-interact; PIN2-interacting protein 1; PIN2-interacting protein X1; PIN2/TERF1-interacting telomerase inhibitor 1; PIN2/TRF1-interacting protein; pinx1 {ECO:0000312|EMBL:ABO28828.1}; Protein 67-11-3; TRF1-interacting protein 1; unnamed protein product
Gene Aliases: 2210403I16Rik; 2610028A01Rik; 67-11-3; AU024023; Gno1; LPTL; LPTS; LPTS1; PINX1; Pxr1; RGD1566025
UniProt ID: (Human) Q96BK5, (Rat) A4L691, (Mouse) Q9CZX5
Entrez Gene ID: (Human) 54984, (Rat) 305963, (Mouse) 72400
telomere maintenance via telomerase
mitotic metaphase plate congression
negative regulation of cell proliferation
negative regulation of G2/M transition of mitotic cell cycle
negative regulation of protein ubiquitination
regulation of protein stability
negative regulation of telomere maintenance via telomerase
protein localization to chromosome, telomeric region
protein localization to nucleolus
negative regulation of telomere maintenance via telomere lengthening
positive regulation of protein localization to nucleolus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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