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Invitrogen
PIP4K2B Polyclonal Antibody
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Product Details
PA5-29372
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PIP4K2B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.83 mg/mL
Amount
83 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, HepG2, Raji.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (92%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; Phosphatidylinositol 5-phosphate 4-kinase type-2 beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PTDINS(4)P-5-kinase; PtdIns(5)P-4-kinase isoform 2-beta
Gene Aliases: AI848124; c11; PI5P4KB; PI5P4Kbeta; PIP4K2B; PIP5K2B; PIP5KIIB; PIP5KIIbeta; PIP5P4KB
UniProt ID: (Human) P78356, (Mouse) Q80XI4
Entrez Gene ID: (Human) 8396, (Mouse) 108083
nucleotide binding
protein binding
ATP binding
GTP binding
kinase activity
1-phosphatidylinositol-4-phosphate 5-kinase activity
1-phosphatidylinositol-5-phosphate 4-kinase activity
transferase activity
protein homodimerization activity
phosphatidylinositol kinase activity
phosphatidylinositol phosphate kinase activity
kinase
lipid metabolic process
cell surface receptor signaling pathway
regulation of autophagy
phosphatidylinositol metabolic process
negative regulation of insulin receptor signaling pathway
phosphatidylinositol phosphorylation
autophagosome-lysosome fusion
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
positive regulation of autophagosome assembly
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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