Immunogen sequence: YFDTETYNAL MKTLQRDCRV LESFKIMDYS LLLGIHFLDH SLKEKEEETP QNVPDAKRTG MQKVLYSTAM ESIQGPGKSG DGIITENPDT MGGIPAKSH
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
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Protein Aliases: MSS4; Phosphatidylinositol 4-phosphate 5-kinase type I beta; Phosphatidylinositol 4-phosphate 5-kinase type-1 beta; phosphatidylinositol-4-phosphate 5-kinase type-1 beta; phosphatidylinositol-4-phosphate 5-kinase, type I, beta; PIP5K1-beta; PIP5KIbeta; Protein STM-7; ptdIns(4)P-5-kinase 1 beta; STM7; Type I phosphatidylinositol 4-phosphate 5-kinase beta; type I phosphatidylinositol-4-phosphate 5-kinase beta
Gene Aliases: MSS4; PIP5K1B; STM7
UniProt ID: (Human) O14986
Entrez Gene ID: (Human) 8395