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Proteintech
PITX1 Polyclonal Antibody
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Product Details
10873-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PITX1 Fusion Protein Ag1303 (1-314 aa encoded by BC009412)
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Amount
57 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDAFKGGMS LERLPEGLRP PPPPPHDMGP AFHLARPADP REPLENSASE SSDTELPEKE RGGEPKGPED SGAGGTGCGG ADDPAKKKKQ RRQRTHFTSQ QLQELEATFQ RNRYPDMSMR EEIAVWTNLT EPRVRVWFKN RRAKWRKRER NQQLDLCKGG YVPQFSGLVQ PYEDVYAAGY SYNNWAAKSL APAPLSTKSF TFFNSMSPLS SQSMFSAPSS ISSMTMPSSM GPGAVPGMPN SGLNNINNLT GSSLNSAMSP GACPYGTPAS PYSVYRDTCN SSLASLRLKS KQHSSFGYGG LQGPASGLNA CQYNS (1-314 aa encoded by BC009412)
Target Information
PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hindlimb expressed homeobox protein backfoot; Hindlimb-expressed homeobox protein backfoot; Homeobox protein P-OTX; Homeobox protein PITX1; OTX; Paired-like homeodomain transcription factor 1; pituitary homeo box 1; Pituitary homeobox 1; Pituitary OTX-related factor; unnamed protein product
Gene Aliases: BFT; CCF; LBNBG; P-OTX; PITX1; POTX; PTX1
UniProt ID: (Human) P78337, (Mouse) P70314
Entrez Gene ID: (Human) 5307, (Mouse) 18740
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription factor binding
sequence-specific DNA binding
homeodomain transcription factor
skeletal system development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
anatomical structure morphogenesis
branchiomeric skeletal muscle development
pituitary gland development
embryonic hindlimb morphogenesis
hindlimb morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
myoblast fate commitment
cartilage development
transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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