This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts.
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Protein Aliases: aphakia; Homeobox protein PITX3; MGC12766; Paired-like homeodomain transcription factor 3; Pituitary homeobox 3; Pituitary homeobox 3 (Homeobox protein PITX3)
Gene Aliases: ak; Pitx3; Ptx3
UniProt ID: (Mouse) O35160
Entrez Gene ID: (Mouse) 18742