Hiwi is a member of the Piwi /Argonaute protein family. Hiwi is specifically expressed in germline cells such as spermatocytes and round spermatids during spermatogenesis. Hiwi is also expressed in CD34+ hematopoietic progenitors, but not in CD34- hematopoietic cells, suggesting a role for this gene in the maintenance of hematopoietic stem cells.
Protein Aliases: HILI; mili; Miwi like; Miwi likw; piwi homolog; piwi like homolog 1; piwi-like 1; piwi-like homolog 1; Piwi-like protein 1; piwi-like protein 2; piwi-like RNA-mediated gene silencing 1; PIWIL1L; piwil2-like protein
Gene Aliases: CIWI; CT80.1; HIWI; MIWI; PIWI; PIWIL1
Molecular Function: translation initiation factor