This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: GIALVHTDSY DPDGKHGEDN DHLQLSAEVV EGSRYQESLG NTVFELENRE AEAYTGLSPP VPSFNCEVRD EFEELDSVPL VKSSAGDTEF VH
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 64%.
Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase Praja-2; Neurodap1; praja 2, RING-H2 motif containing; praja ring finger 2; praja ring finger 2, E3 ubiquitin protein ligase; Praja2; RING finger protein 131; RING-type E3 ubiquitin transferase Praja-2; RNF131
Gene Aliases: KIAA0438; Neurodap1; PJA2; RNF131
UniProt ID: (Human) O43164
Entrez Gene ID: (Human) 9867
Molecular Function: ubiquitin-protein ligase