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Invitrogen
PK2L1 Polyclonal Antibody
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Product Details
PA5-51256
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide of human PKD2L1
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Amount
150 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total PKD2L1 protein.
Target Information
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ion channel; PK2L1; PKD2b; Polycystic kidney disease 2-like 1 protein; Polycystin-2 homolog; Polycystin-2-like protein 1; Polycystin-2L1; Polycystin-L; Polycystin-L1; similar to PKD2; transient receptor potential cation channel, subfamily P, member 3
Gene Aliases: PCL; PKD2L; PKD2L1; PKDL; TRPP3
UniProt ID: (Human) Q9P0L9
Entrez Gene ID: (Human) 9033
calcium activated cation channel activity
cation channel activity
calcium channel activity
sodium channel activity
calcium ion binding
protein binding
cytoskeletal protein binding
cation transmembrane transporter activity
calcium-activated potassium channel activity
sour taste receptor activity
identical protein binding
actinin binding
ion channel binding
metal ion binding
metal ion transmembrane transporter activity
muscle alpha-actinin binding
alpha-actinin binding
pH-gated monoatomic ion channel activity
osmolarity-sensing cation channel activity
detection of chemical stimulus involved in sensory perception of sour taste
ion transport
cation transport
calcium ion transport
smoothened signaling pathway
response to water
ion transmembrane transport
sodium ion transmembrane transport
detection of chemical stimulus involved in sensory perception of taste
sensory perception of sour taste
detection of mechanical stimulus
protein tetramerization
protein homotetramerization
calcium ion transmembrane transport
cellular response to pH
cellular response to acidic pH
potassium ion transmembrane transport
cation transmembrane transport
inorganic cation transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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