Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC delta is one of the PKC family members, and may play a role in antigen-dependent control of B-cell function.
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Protein Aliases: nPKC-delta; Protein kinase C delta type; Protein kinase C delta type catalytic subunit; Protein kinase C delta type regulatory subunit; protein kinase C delta VIII; protein kinase C, delta; Protein kinase C, delta typen; SDK1; Sphingosine-dependent protein kinase-1; Tyrosine-protein kinase PRKCD
Gene Aliases: ALPS3; CVID9; MAY1; nPKC-delta; PKCD; PRKCD
UniProt ID: (Human) Q05655
Entrez Gene ID: (Human) 5580
Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase